On behalf of the organizing committee, we are delighted to welcome you to Caparica, Portugal, for the I International Symposium on Profiling, ISPROF 2013. The Conference will be held in Caparica (Lisbon, Portugal) in September 2013 during days 2nd, 3rd and 4th. We cordially encourage you to attend and contribute to one of the major events of 2013 on the field of profiling. We are confident that you will appreciate the scientific program and the city of Caparica. Symposium Subjects: Profiling in Proteomics, Metabolomics, Biomedicine and Clinics, Genomics, Environmental Analysis, Food Science; Statistics and Informatics for Profiling; Technological Advances in Profiling; Sample treatment for Profiling; Monitoring.