The scientific principles related to the optimisation of chemical processes so that they can be transferred from the laboratory to plant scale with minimal risk is an often underappreciated aspect of process development chemistry. Relevant physical organic chemistry principles are not widely taught in standard academic chemistry courses and are generally gained with experience – either through knowledge transfer within companies or through trial and error after mistakes have been made.
Based on the work of Prof John Atherton, this course provides an introduction to some of the key physical organic chemistry principles that underpin chemical process development as well as the requirement for inter-disciplinary cooperation i.e. process development chemists, chemical engineers, analytical chemists etc. The theoretical concepts are supplemented with numerous examples to demonstrate different aspects of the relevant single- and multi-phase physicochemical science, exploring the potential impact of various phenomena on yield, selectivity and reaction rate.
Based on the work of Prof John Atherton, this course provides an introduction to some of the key physical organic chemistry principles that underpin chemical process development as well as the requirement for inter-disciplinary cooperation i.e. process development chemists, chemical engineers, analytical chemists etc. The theoretical concepts are supplemented with numerous examples to demonstrate different aspects of the relevant single- and multi-phase physicochemical science, exploring the potential impact of various phenomena on yield, selectivity and reaction rate.
