Nate Adams University of Sheffield
Title: The active site of magnesium chelatase
Abstract: The insertion of magnesium into protoporphyrin initiates the biosynthesis of chlorophyll, the pigment that underpins photosynthesis. This reaction, catalysed by the magnesium chelatase complex, couples ATP hydrolysis by a ChlID motor complex to chelation within the ChlH subunit. We probed the structure and catalytic function of ChlH using a combination of X-ray crystallography, computational modelling, mutagenesis and enzymology. Using this approach we have determined the binding site for porphyrin, and the key residues involved in catalysis.
Time: Nov 25, 2020 04:00 PM London
Join Zoom Meeting
https://swanseauniversity.zoom.us/j/94065264416?pwd=NC9VOExFQ3ZCcTZEeThlMDM2N1lxUT09
Meeting ID: 940 6526 4416
Passcode: 643422
Title: The active site of magnesium chelatase
Abstract: The insertion of magnesium into protoporphyrin initiates the biosynthesis of chlorophyll, the pigment that underpins photosynthesis. This reaction, catalysed by the magnesium chelatase complex, couples ATP hydrolysis by a ChlID motor complex to chelation within the ChlH subunit. We probed the structure and catalytic function of ChlH using a combination of X-ray crystallography, computational modelling, mutagenesis and enzymology. Using this approach we have determined the binding site for porphyrin, and the key residues involved in catalysis.
Time: Nov 25, 2020 04:00 PM London
Join Zoom Meeting
https://swanseauniversity.zoom.us/j/94065264416?pwd=NC9VOExFQ3ZCcTZEeThlMDM2N1lxUT09
Meeting ID: 940 6526 4416
Passcode: 643422
