91AV

Introduction

The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. It is now emerging that the modification status of the transcriptome is dynamic and responsive to environmental/developmental cues. Together, this has elicited the realisation of an ‘epitranscriptome’ where post-transcriptional RNA modification coupled with recruitment of effector RNA binding proteins dynamically regulates genomic output. Importantly, mutations in setting or reading RNA modifications are causative of many human diseases or congenital disorders. This meeting aims to explore all aspects of this emerging topic, from methods development to molecular mechanism. Most importantly, the meeting will place an emphasis on the contribution of RNA modification to mammalian development, tissue homeostasis and disease.

Deadlines

• Jan 29 2020
  Abstract deadline

  
• Mar 11 2020
  Standard registration deadline

  

Useful links

Venue

EMBL Advanced Training Centre

EMBL Advanced Training Centre, Meyerhofstraße 1, Heidelberg, 69117, Germany

Contact information

EMBL Events
+49 6221 378 8797
Contact us by email

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