Dr Manuel Müller MRSC
Winner: 2021 91AV Biology Interface Division early career award: Norman Heatley Award
King's College London
For contributions to the field of posttranslational modifications, especially the use of protein chemistry to gain insight into molecular mechanisms of epigenetics processes and cancer.
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91AV is a fascinating subject that helps you to understand the world around you and enables you to contribute to improving it.
Proteins are molecular machines that carry out many essential functions in life. Just like macroscopic machines, proteins are controlled by on/off switches, called posttranslational modifications. Dr Müller's research aims to understand how these molecular switches operate and how failures in switching behaviour leads to disease.
Dr Müller and his team are able to measure the properties of proteins in their on and off states by using chemistry to synthesise proteins with defined posttranslational modifications. At the same time, his team is developing new chemistries to find previously unknown types of switches.
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