ࡱ>  bjbjVV )<<  8'Dk<*))))))),.)4r"44))V!V!V!4x)6V!4)V!V!:'',g'O jS' o))0*]' @/!@@/g'g'@/{':V!b))V!*4444@/ : The 91AV Industrial Affairs Division 22nd Symposium on Medicinal 91AV in Eastern England Thursday 19th May 2011, Fielder Centre, University of Hertfordshire Organising Committee: Dr A Faller (Eli Lilly), Dr N Hamblin (GlaxoSmithKline), Dr J Macritchie (BioFocus) MORNING PROGRAMME Chairman: Dr Angus MacLeod (BioFocus) Rapid Discovery of DP1 Antagonists with Good Developability Characteristics Matthew Crawford (GSK) The Identification of Clinical Candidate, AZD8055: A Potent, Selective Small Molecule Inhibitor of mTOR Kinase Kurt Pike (AstraZeneca) Aldehyde Oxidase Metabolism: An Emerging but surmountable Problem in Drug Discovery Thien Duc Tran (Pfizer) AFTERNOON PROGRAMME Chairman: Prof Robin Ganellin (University College London) Optimisation of CHK2 Inhibitors by Structure-based Design John Caldwell (Imperial Cancer Research) Heterocyclic Inhibitors of the CFTR Chloride Ion Channel as Potential Treatment for Acute Secretory Diarrhea Kevin Doyle (BioFocus) Discovery of Orally Active, Selective S1P1 Agonists Jack Brown (GSK) Rational Design of Small Molecule Neuropilin-1 Antagonists Trevor Perrior (Domainex) Registration form available via the RSC website http://chemistry.rsc.org/ConferencesAndEvents For further information contact: Dr A.Faller Eli Lilly & Co Ltd, Lilly Research Centre, Erl Wood Manor, Sunninghill Rd, Windlesham, Surrey, GU20 6PH Tel: 01276 483036. e-mail: HYPERLINK "mailto:faller_andrew@Lilly.com"faller_andrew@Lilly.com 22nd SYMPOSIUM ON MEDICINAL CHEMISTRY IN EASTERN ENGLAND Organised by the Biological and Medicinal 91AV Sector of the 91AV Industrial Affairs Division 19th May 2011 Fielder Centre, University of Hertfordshire, Hatfield, Hertfordshire, UK REGISTRATION FORM Fees, including lunch: RSC Members: 75 ( Non-Members: 90 ( Students/Retired Members Free ( Please tick appropriate box and enclose cheque payable to "RSC-BMCS" SURNAME ......................... 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