ࡱ> %` 6"bjbj .H̟̟6dddddddx\\\\\4x$6g$i$i$i$i$i$i$$'h)~$d"""$dd$C#C#C#":ddg$C#"g$C#C#ddC# z\M":C#K$$0$C#*"*C#C#*dW# C#\$$9# $""""xxx\xxx\xxxdddddd  Organic Division: Heterocyclic and Synthesis Group Chairman: Dr John Clough Secretary: Dr Karl Hemming Principal Scientist Division of 91AV Syngenta University of Huddersfield Jealotts Hill International Research Centre Queensgate, Huddersfield Bracknell, Berkshire HD1 3DH, United Kingdom RG42 6EY, United Kingdom Tel +44 (0)1484 472188 Fax +44 (0)1484 472182 E-mail: k.hemming@hud.ac.uk Committee: Dr John Clough (Syngenta, Chairman), Dr Karl Hemming (University of Huddersfield, Secretary and Treasurer), Dr Martin E Swarbrick (GSK), Dr Adrian Dobbs (Queen Mary, London), Dr Robert Stockman (Nottingham), Dr Judy F Hayler (Novartis) Notice of Meeting 23rd Postgraduate Heterocyclic Symposium, Thursday September 18th 2008, GlaxoSmithKline, Stevenage, Hertfordshire, UK The 23rd Postgraduate Heterocyclic Symposium of the Heterocyclic and Synthesis Group will be held at GlaxoSmithKline, Stevenage, UK on Thursday September 18th 2008. The meeting will start at 11.15 am and close at 4.45 pm. Coffee will be available from 10:30 am. Lunch will kindly be provided by GSK. The main lectures will be given by: Prof. Dr. Erick M. Carreira (ETH Zrich) Discovery and Surprises with Small Molecules Dr David R Spring (Cambridge) Search for New Antibacterials Using Diversity-Oriented Synthesis" Dr David House (GSK) Palladium-catalysed cascade approach to saturated ring systems There will be five lectures given by postgraduate students. There will also be a poster session for postgraduate students during the lunch interval. If you are a postgraduate and wish to speak or to present a poster, or if you wish to nominate a postgraduate speaker or poster presenter, please let me know on the attached nomination form. A registration form is attached. For reasons of security, it is essential that all participants register. If you wish to take a car on site, it is important that you also let me have your car registration number. To get access to the site on the day you will need a letter to confirm that you have registered for the meeting. For this reason, all registrations will be acknowledged please ensure that you bring that letter of acknowledgement with you on the day in order to gain access to the site. Travel information will be e-mailed out to registered participants. Karl Hemming June 2008 91AV, Heterocyclic and Synthesis Group 23rd Postgraduate Heterocyclic Symposium, Thursday 18th September 2008 GlaxoSmithKline, Stevenage, Hertfordshire Registration Form Name [and title]: Affiliation: (e.g. name of company, university etc) Postal address: E-mail: I would like to reserve a parking space: YES or NO (please delete) Car Registration Number: Special Dietary Requirements: Please include me on the list for the 23rd Postgraduate Heterocyclic Meeting, 18th September 2008 I enclose my remittance as indicated: Heterocyclic/Synthesis Group Member 15 Non-member of Heterocyclic/Synthesis Gp 30 TOTAL: Non-member of RSC 40 Student Gratis Please return this form not later than 5th September 2008, with remittance to the Secretary: Dr Karl Hemming, Division of 91AV, University of Huddersfield, Huddersfield, HD1 3DH. Cheques should be made payable to Heterocyclic Group. The Heterocyclic and Synthesis Group is not registered for VAT. If you are a postgraduate and wish to speak or to present a poster, or if you wish to nominate a postgraduate speaker or poster presenter, please let me know on the attached nomination form. Karl Hemming June 2008 91AV, Heterocyclic and Synthesis Group 23rd Postgraduate Heterocyclic Symposium, Thursday 18th September 2008 GlaxoSmithKline, Stevenage, Hertfordshire Speaker and Poster Nomination Form The Heterocyclic and Synthesis Group of the 91AV is holding its Postgraduate Heterocyclic Symposium on Thursday 18th September 2008 at GlaxoSmithKline, Stevenage. A plenary lecture will be delivered by Professor Erick Carreira (ETH, Zurich) with supporting lectures from Dr David House (GSK) and Dr David Spring (Cambridge) together with the five postgraduate lectures. The meeting will start at 11.15 am and close at 4.45 pm (coffee from 10.30). There will be no registration fee for students, but please note that all participants must register on the accompanying registration sheet. Morning coffee, lunch and afternoon tea will be provided. Travelling expenses and, where appropriate, overnight accommodation for student presenters will be provided. Student talks will be 20 minutes including 2-3 minutes for discussion. Lectures/posters on any aspect of heterocyclic/synthetic chemistry will be welcome. We also hope that you will encourage other students in your department to attend the meeting to support the presenters. I thank you for your help in advertising this event and please get in touch if you require any further information. --------------------------------------------------------------------------------------------------------------------------------------- Nomination Form for Speakers and Poster Presenters The postgraduate student should complete this form and return it (together with a one-page abstract abstract by email) to Dr Karl Hemming, Secretary, Heterocyclic and Synthesis Group, Division of 91AV, University of Huddersfield, Huddersfield, HD1 3DH, as soon as possible and not later than 11th August 2008. (E-mail:  HYPERLINK "mailto:paob1@york.ac.uk" k.hemming@hud.ac.uk; Tel: 01484 472188; fax: 01484 472182). Five speakers will be selected by the Committee of the Heterocyclic and Synthesis Group from those applying to present a talk. If you are not selected for a talk, it is hoped that you will come and present a poster at the meeting. It is also possible to apply to present a poster only, although space is limited. 1 Name of student and e-mail address: 2 University/Department & Address: 3 Supervisor: 4 Please indicate whether you wish to present your research as: Talk: YES / NO Poster: YES / NO 5 If not selected to present a talk, are you willing to present your research as a poster? YES / NO To enable the committee to select the speakers and poster presenters, please: e-mail a one-page abstract to Dr Karl Hemming. The abstract should indicate the title, the students name, the supervisors name, the University/Department and would typically be ~100 words with appropriate structures. The abstracts will be used in the meeting booklet. Deadline for nomination form and abstract: 11th August 2008 79:CDRVWabeqr  & + _ ` v z } øxkkh72hCJOJQJhgCJOJQJh3CJOJQJhn~CJOJQJh72CJOJQJ hn~6CJhCJOJQJ h726CJh726CJOJQJh72OJQJh72>*B*phh72B* CJ,OJQJphhV:h72CJOJQJjh72CJOJQJU*79:r 9 : k l $a$gdk![gdk![$a$gdk![gd 1 d1$gdhP d1$d1$ (1$d$a$6" - / G   ϼ{k[kK9K"hV:hV5CJH*OJQJaJhV:hV5CJOJQJaJhV:h'5CJOJQJaJhV:hk![5CJOJQJaJhU6hhP5 h 15 hc*b6 h 16hcnh 16CJ h 16CJhcY^h 156CJhhPhK@CJOJQJ$hU6h>*B*CJOJQJphhU6h72CJOJQJhn~CJOJQJh72hCJOJQJh72h72CJOJQJ  8 ? B @ M U X d g ѳ””³q`P@hV:hV5CJOJQJaJhV:h'5CJOJQJaJ hV:hA CJOJPJQJaJ hV:hVCJOJPJQJaJ#hV:hV5CJOJPJQJaJhV:hhPCJOJQJaJhV:hVCJH*OJQJaJhV:hVCJOJQJaJhV:hk![CJOJQJaJhV:h'CJOJQJaJhV:haOCJOJQJaJhV:hk![5CJOJQJaJ L <=ABCdf$a$gd3$&dPa$gdk![ P^`Pgdz" P^`Pgdz" $ a$gdk![$a$gdk![   K L Z _ a c :h~n^nNn?hV:hc*bCJOJQJaJhV:h35CJOJQJaJhV:hhP6CJOJQJaJhV:hk![6CJOJQJaJ"hV:hk![56CJOJQJaJ"hV:hVCJOJQJ\]aJhV:hz"CJOJQJaJhV:hk![CJOJQJaJhV:hVCJOJQJaJhV:hV5CJOJQJaJhV:hk![5CJOJQJaJhV:h'5CJOJQJaJh"@BCO\^bcdef'(ô񖴖yiy\ôLhV:hc*b5CJOJQJaJhV:h3CJOJQJhV:h35CJOJQJaJhV:h35CJOJQJhV:hc*bCJOJQJaJhV:h%sCJOJQJaJhV:h3CJOJQJaJhV:hk![CJOJQJaJhV:hk![5CJOJQJaJhV:h{CJOJQJaJhV:hCJOJQJaJhV:h,CJOJQJaJ'(@ABOvwxgdk![$a$gdk![gdk![$a$gdk![$&dPa$gd3$a$gd3(8?BOvx@PtteXKhV:hc*bCJOJQJhV:hk![CJOJQJhV:hCJOJQJaJhV:h4Q^CJOJQJaJhV:h,CJOJQJaJhV:hc*bCJOJQJaJhV:h{5CJOJQJaJhV:h{CJOJQJaJhV:hk![CJOJQJaJhV:hc*b5CJOJQJaJhV:hk![5CJOJQJaJhV:h,5CJOJQJaJ|}~012ef&'()J$a$gdk![dgdc*b$a$gdc*bdgdk![$a$gd,$a$gdk![gdk![PQgiy{|}~02Y\ʹʙyhYI9hV:h5CJOJQJaJhV:hc*b5CJOJQJaJhV:h,CJOJQJaJ hV:hhPCJOJPJQJaJ hV:hhPCJOJPJQJaJhV:h4Q^CJOJQJaJhV:hc*bCJOJQJaJ hV:h,CJOJPJQJaJ hV:hc*bCJOJPJQJaJhV:hk![CJOJQJaJhV:hc*bCJOJQJhV:hk![CJOJQJhV:h,CJOJQJ\jk~"5Ccdf$&JKТГІyi\NhV:haO5CJOJQJhV:haOCJOJQJhV:h35CJOJQJaJhV:h3CJOJQJhV:hk![CJOJQJhV:hhPCJOJQJaJhV:h,CJOJQJaJhV:h%s5CJOJQJaJhV:hCJOJQJaJhV:hk![CJOJQJaJhV:hV5CJOJQJaJhV:hk![5CJOJQJaJJKLstBCCvw#$_$a$gdk![  >gdk![$a$gdk![$&dPa$gdaO$a$gdaO$&dPa$gdaOgdaOKL$,T񶤒xxxkkƅk]O]hV:h6CJOJQJhV:hk![6CJOJQJhV:hCJOJQJhV:hVCJOJQJhV:hk![CJOJQJ"hV:hk![56CJOJQJaJ"hV:haO56CJOJQJaJhV:haO5CJOJQJaJhV:haOCJOJQJhV:haO5CJOJQJaJhV:haO5CJOJQJhV:haOCJOJQJaJTrtuB^_tu29RSVbdy毟ssbb!jhV:hk![CJOJQJUhV:h%s5CJOJQJhV:hk![5CJOJQJhV:h56CJOJQJhV:h56CJOJQJhV:hk![56CJOJQJhV:hwCJOJQJhV:haOCJOJQJhV:h3CJOJQJhV:hk![CJOJQJhV:h%sCJOJQJ#  !"J^  k !!!!$"&"3"4"5"6"ӹӬӟӟӒӒӒӒӃhV:h72CJOJPJQJhV:hhCJOJQJhV:hhPCJOJQJhV:hCJOJQJhV:h,CJOJQJhV:h%sCJOJQJhV:hk![CJOJQJ!jhV:hk![CJOJQJUhV:h%s0JCJOJQJ_` + , @!!!!5"6"$ LT(#1$7$8$H$a$gd-zgdhP $ a$gdhP gdhP $ a$gdk![$a$gdk![,/ =!"#j$% $Dd 09f  C 4ARSC_logo_mono"`RjH.E4)FDF>H.E4)JFIF,, _ExifMM*bj(1r2i,,Adobe Photoshop CS Windows2005:06:01 10:12:20r[&(. )HHJFIFHH Adobe_CMAdobed            " ?   3!1AQa"q2B#$Rb34rC%Scs5&DTdE£t6UeuF'Vfv7GWgw5!1AQaq"2B#R3$brCScs4%&5DTdEU6teuFVfv'7GWgw ?3wVY7d ǯ&v k"grzwS陙7`dtܛ{fNz=_D':mS`Kk}t Zn_9?X 6,sOGSsAtNOSvtdTM̏ 6,UdQ\v. cߝZ+_YtmTKked=hu/Yp_!cTZ6Ɋ*ח߃} JJzoY;33Dz.{gomkwKG}H#nKKk2s||Vlo'ӯkpzUO:v߈2ؽa%8TwJ5tۇKCv ,{߿s*O[>/ft\'lg[]d骏INOTY :oob2h[}3v~.Ȳz[n%xk8]'m}'?Vt&[wG^7.1m[hzwY4Wz+"dkaf?ZJrݗc]20h{zʟ5׎ǦﱙU}T<[K Feϳ.p nV]llX5e^5WEwLבUXS\ƑihknM7(t~1pӰ͌kH,A~S׺SɯlLʫ̛Waʻ21l:g}|ZKzʶV=?CPcmn1cU=} K?G]gG=N .,mm-{ﵹ{~pswy_s^+kqjeoY[wZkdlo%<_Zzf#[ngc-{luxmv.+_ӭ̋~GGK}OzOAȯ ~(uFƟZkm/ uѰ2.?LȮqv'/]u}9rl z>5ݏ6ܱǩ첵FO%NN3GOΠV3g]^웾Wef.&igգdb+շԡɯgMsvWfUVKLsqq)*ޭձs79#)I$2NEmQoTz^__Ecdt_3gvc{]j._]ůȯWJߗ_RIOT~ Թ k}Q6z{YGJU虝?M.#39ſ.ͬ~P6Y_S9es-MU[߿ @`~$^vONmWl˧8V673՛u7]MVX=#&ޚ7;cY} *ݍO5c3_V9$fpFW:ЅMճ*̋qlo9/zVyOךk{2+c!DZWg_df7"ϰz>깔۱ճI)3S?ʱϋ]/ft\'lg[]d骏INOTY :oob2h[}3v~.Ȳz[n%xk8]'m}'?Vt&[wG^7.1m[hzwY4Wz+"dkaf?ZJrݗc]20h{zʟ5׎ǦﱙU}T<[K Feϳ.p nV]llX5e^5WEwLבUXS\ƑihknM7(t~1pӰ͌kH,A~S׺SɯlLʫ̛Waʻ21l:g}|ZKzʶV=?CPcmn1cU=} K?G]gG=N .,mm-{ﵹ{~pswy_s^+kqjeoY[wZkdlo%<_Zzf#[ngc-{luxmv.+_ӭ̋~GGK}OzOAȯ ~(uFƟZkm/ uѰ2.?LȮqv'/]u}9rl z>5ݏ6ܱǩ첵FO%NN3GOΠV3g]^웾Wef.&igգdb+շԡɯgMsvWfUVKLsqq)*ޭձs79#)I$2NEmQoTz^__Ecdt_3gvc{]j._]ůȯWJߗ_RIOT~ Թ k}Q6z{YGJU虝?M.#39ſ.ͬ~P6Y_S9es-MU[߿ @`~$^vONmWl˧8V673՛u7]MVX=#&ޚ7;cY} *ݍO5c3_V9$fpFW:ЅMճ*̋qlo9/zVyOךk{2+c!DZWg_df7"ϰz>깔۱ճI)3S?ʱϋ] 4294967295 626 91 1 300/1 300/1 2 2005-06-01T10:12:20Z 2005-06-01T10:12:20Z 2005-06-01T10:12:20Z Adobe Photoshop CS Windows uuid:26b98e84-753a-11d9-8a8c-f1d9bfa449e9 adobe:docid:photoshop:3a4cc2be-7539-11d9-8a8c-f1d9bfa449e9 adobe:docid:photoshop:41e9eb27-d27d-11d9-8b8d-8f4ba0cea9df image/jpeg !AdobedC [r    908 1!67*:@A54')   ! 1"AQ#678x90aq45f 23c$Td%Ue&V'g(:@BCGWwHXhbEuFvRSD)Y|9 z-Џj|xv IǙ/띉[!Ƅ|tr<TrmhG2澷:YQNuBD +<*y^D&vHzZ U})-̫Y`g .@f˯LĕZgSR[K5%1ۦI_L릀C67@" {LLwx҇17ZtG*c6R,i WB tazx^^]@ Ԕn""~Ǹ{mz'T+ų -2Ww/s8jt]wcNݛr|T@^ [7J5%0۪Irb2˼+Ha vD*MIu_[6}:s+դ+Wn̟ Ȣ@ oOujJ`ݿ|GAKx?|!N.cKyd|K-c fE.3R_TcY6޳$cit`杄ˣ#Uy55/۪I+vbJ7@rU1曁 fE -JTiBD``6 '07txjJcL]%fzR"ZiF " {L4&BW',#lI=l?K`jĥC'qse9͋w&f6FDi {ZMmޕQKR$,}d-Q Bi@p .TA Ӎ>uiGk9EK&P0Ze?jg~p{Pa+7~lk8u fBݮٚ]iAz9g5BOٙ]V44GJl24L(3d`:7)䗊~G55r,w^I$ݍ4h7ZP( VYEkA '!jtun6OKANy(9_,-YT<9xlʫ$GyhCKٮNijo;vV\&+:ylB~jd^\u*k+0!ѽx2Q`ȝw5gzḮ ˛H%K& bk`l3x0Sf \[1bYg>Ge짊J"0UUMCȬ.7LIoA#0P'5Ɯyq8ܞ&'IH1B $QL"d<=cI{f{[0O[M58ܒ\J>Y9?ak%1Sii˾ɥElōS@I-aofwvޛ컏e{)7#J11PR*w`b'ҝUU)lj=f3{oZ \N'D6oL|<˛)%oE\ &2Tʌٮ63`tLƁ֊RQ,w[)78Ix'Q3~0x ;ߛzCqqHnJOawP{uoxPYBud_: 3c=vLjݨvhm8h!~jy;HlڈXˬ41Ms m6fQhX8FY3iAe왲ӦzSيFy+&e1*lNX/0ׁĨ6۲h:D;ƶɨT%lёFX:X5< ?gUX GTwXJ- =3D\;{5 ~؃uv{#++VK6Jx B9 c; ģ)iwQvM_: 0xOlwʭ`PjK/t8bx77tk%fǷ;:W3nYnCj%G=^v|@G)[~BXԵXA6'md5ua0ʹ+XʈNW Df3̆XRRaF3QrEƣ75l_)f1B_UȾqݨkOsּ<>.:ǵV+5ư**rq>m:hqO?8¡(Yh9'!7sU?whuUхW&O/LGx̝۞ȳ# *s 32j-c.D: ^'E{K+\jV}Hu"qݨkVIYSrMǑ11)Zc80"bcV$'#R9ͷFQL?,Qv=_:=h+Ԡ. I6*K6'w~T틜a\ ?rΧ1 sJ7*ӶiFY- K?Jq=w~=taUxo PrYS:u~ F!Wi9]8] M$:mrl̻KH&1E4:y|^7 胎,F Qm*VǽUbc U^6qCL+sIQ9)D|| W)ڋ%cD"*{7׋aSc[Py"xx&4R }]{IAY،Y`Pb=rTc@g1[$SPTSREzj0x4ʡVlU*]ptմ!d&7tEl(qLy]Ry)l"\bDUvCEeVRo魗M$M80 p2nFrSzJ烇sX<Mq<Jϐ~b.4þ.>~>4~I&:$?0O~0;>ro?ts-ofOFǥPcfRa[;>GkkƎ!3̳Y3A>[/!#^h~ZAa2cECΎɞyo>??6y>[i_?VjR;oLΜFёk7"fx&'X RY0 KO[/U,EPQ5S:j&p9qG bn ñyj5\;6`9KѢ%9@Hrza9tm\~'2C_i(Sj7*n"xc d1ɴu,IRŲ( }UT'0kYSjy;XNw+SLC%bpUH讗*%JErёMFRa- LH:v -8)/*TYfp 7,cݳ!a/#f $e$"Ih)e&$ጕsA8U:VڠWgee킕 dra6G49eL!IhWEZ+I>gQt[0YxLjv 6*܊`ۉ}43CYE3֣A'$}+iSuLD0( o@sg 섭OZgxh,D}X D@flR:{vuڍx*CRi7VY٥Sg?MECGGL IxfÉGzԴXrU8QBB_!,;PA*21AA`ƷΒҮѽ_@jɗjX?uJy{Q!@:w $],z`^<$tӱXN@5YLz DHfE$ge1J[;@MS`w;eY1PLL] {=d^ 䕯1Wy$߄Q@t"\Lͼ^H$ռM;̵)ޑcҪTo0L$$H0 ۀ@7U4mo'v8Dk1C*%[Rs)ɠ%-A)ʯէPyZ7_DBV6ܔkO;6]nSr{mJy,WFZnrbAtVZMڮ.eU8G|8ACg\$<̥fpF3c }mQ#(9pbjOֺo]ɘdqKȒYJFMA֘zJH+b9,U;!jQnC|:m`,QۆqR F!1DDQ,ԔWNv D$T-)yB2*I]WF@,uV)j֫QJbzz]8UܸU$QLcvL{3Գd2bIiͥ::ijЖD%Acr6׼4vrshc:NPM7Ig8mT<[l4ɳ7vm)e;U B ;o?iN>#N(~6Ky򀩆^3o@z7NiOۃ>}dZEB^X27Z5N$̑s11Ģ"Am?-s9^0|: ܨ$Y D2Ї: Gen*i3yfn6Z+*"5U~A̒JsIP:dvrh҅}$.Ò)&_ՠT_C@B4aלA6sq,mC0@F+ePd װL`ɤ RI l-T'y÷ _`ùjL~‘rY]5ЮP@JuYx;`~O'H ĨElW2'QeCEr,>tEcࢱ sp&bݤʝk g<[[u/c2f!2eLEsU*bR^)̦FWd85ÑKӴ^2;X$.]c lڻ:N uwU5iZ5zcX S(I1U&$A$@\SRQFڋðZyp57{m"dXѐdPw&+ "4C 6T>h929%e֤R?EY=KnQS"Vc78\umI5^7/Ud79i*昬c! 2ZͶD^zi\bM$7Q1w4[sIKH&ՋS+\eyQmtz&W})^ qhq^'jbGY#EY9ȽDw^$!,Oi{F/c:M*n&JZͩOH7۲od8n hwn-=VAfYn?j>L ǒ J1 ecudkvQ(㪱Oٮ̐'|@, ~ה-ZZJcV),2=$T`V c3>z5b[åj;Xi=cYnk*db˜.Sz[>11QN͝`h ReV4=4foPDUHTnEu!d3K^2xZ2 xhλ|GhI&-*w T7zwICuV-nѓj79DpѠ5}M.NUœ/(="Ķ.ʋa&[,Uz-^9X<9,]|)RtLTFvm;%lygvd>A~WSrO楧4"6Hi>lnF!6ވom{E1 pǼ\yf[3-y+rjeEgTR(e"[:*DWlOXFU{M˕:,>[Ow׏M'vLxu3K]fNVL"Ѫne1HB9p"d!C9@! aWM >H=~ћt<{~]*rijpFUdJQ1{z: FҲ4kUEeANOb =RjsHsrBv&*e5,pD Ru 3i\ѵX!(bpi'3b~h7 lfQGGg5!|ovDu%Ri,'5"ձ D@YlŋZjɎF_][2zҲ %|+YD`̌a]sNڜ`9 <ӆ=m7EJĕ&ؤYWV()qV s'f8&G%妨y[0M5X<-w%;(FlV]/6146ntٿа_N[::5g[oJ&0tSH432U[?2$rf22$R1ݼǿ;:woNX?ó'JEŽTw MHH6:9a^آO i0P N]#mW JsOHXe8[p"a 퐗&Ӭ4sPz"ϓ"8!,w&WMvfWR'|)ΐp2mdra+vgNݬNu8]seLeV]U '1"&:uxgKVpx*Q7C92/8EN )@HfJ-RrݛѿYKПL?q*GD@C NHL?!ͭma #HU 5!vMta^z ]'jpCm+RRZ-Ixr 2gzqFv, w>XoL5qEYjiZkM,\.3܂WY v֮r$B!2%$S~ګՅ³fʸC\S!/1[|M^a ,Y3`W'-XPSz63+37oǖ'RZZlU׹"ΣX`! bBg *!v@*@TӺw6%RиաYbxO)2'̝Uw jo<ɀ uZJ'G=Tbm,.H!@3)&)wk&i:0Ȭܝ7/B㌙Tl$AEu1 ƨfn$]2"kGDcs=ĵ#aYK$/"n7AV&%o9*k] %rL-d|HfKqr**Lq#tTA"gY (k'f(8VtO߶40ƄkVSA25>ȤJܤ<1oY(-RgU-ПL?q*GiJIV-U׵5n&&`atߴd]vTI`KW`ڀʸٖYd_r~KvF|F9鈦N+`S"a8H2>6))6!:0̍79k^2*հ>2#~"%45,576'ĉ9?)ͫS=(E1)³8騳3ܴ˷;21tE>U93"ڛ:x۬P2=貵$eEH/V;nTMT$PD1s|_6fvT6Ϲ_nOcӂz=eiE: -9ƸˆI1rEȡQS|AhU^EdNAvq=6ORrjoQlfZ.IJr*2^N04N]-W׫pڿIܲ^ΉEw'(`SkӋ]G 5#&( !3*=ŌcWSBch lFɱscĄrT @HQ_Nt`1w|]g#䢝m exUVIGhY G2Ǘ8*;MLNn!lL!-Vq51Bu o.1F%"ٓ B;z&ACv&0b*BȨIӪp#Vif%S$A1DJQ`d=CGOHjopc{iSۃ>5lZز20oD[@tb%޾th7IUB@QX@(TW%MܓS$W аڦe'$"ܑ&͋׃Y )Y@Ǖ6UYTp~r,7[ iʛEH*s|f6Fjequ?Df\|םu6e9%U#*A(@]E{3*A߶Mx1SCcn;Z"&Փ5QpkXQpLX&%8ȸm## >9$ٛ&L64nSM4L(x> vfoW t6Y+KM毝* 7)U8 Q)`&'aJc!sBx+x@LY;\)y}‹7XRUGw1^hJF=ڰs$GN*ƙE@riLMw\͔<E&k5uVg fzQL:l uH+&+z3i~mӷL˚Ƴ. I8՚Tjl{]F6RsLUQٝPaRQJVh,V+2w}%$q8RGP:aggWX1mIygK˪ɠ$/h/1b$; Ky[e7KĻ6M!U`fbWo!6k(`b eJ #w^3ƝfMڐsGY1"U{8E*E2ۀu Ky[e7KD6-!Ufb\7Fk*br%)J #wEV!5)U U';uO]u=TcS xZp,QQ3,]r:IS)kURYpܹA@$c,e%jyL~Pk1L6 r:єa\MEN)pV(ijR讜D@Il\NbdTeLM_Hrs9i+^qEԈye"F6T[lEͨmGkWKYXt@R#,Jj:s7;ՐFe#Vn$k  KweHM#1 _ڐP 1G1%X!LK"Q*preo3WCDdNES0`*mX]ݝᕼ]O7 kaT~~jY2Y$RUr>BCq܀Lw}d\pV=-n^9 5mwzV>Kr}ܮ!ɂa.X=O{?x@{#lobHkBP#dgI0W㫬޿#iەQPL@9 :`)c׎y ˛)" Nf:oU99Ui"fpqRj)RnAG1D! 2ri]1NJY.b7YJefhUNR*x#w9/;[# 5sbbd'hbG<6I,KgW]T3珔nDMBD!r(P:gL(8(mcR=9eEK179%;* 7*>(4cT!:ˣ!;´<{IB#K1)Cyԍ|!N=xwx{Dm>[ȰDamI*ܷUP3ǮR@#ȳ7ioMdAYpq0N(xXc1a Hgư(+ukH'9 hWD'mU[,S 喷&n`lɈ9eb,E[AUY3a\3MݕmbU2%#Ngڝ00߰{>.?;h.=Ih &ZmF VEbϢ"2"b0mOtE [G=N=Y˽sX4kiIl%G.EILLr$3TfM4Tוs*ۃܐ?hD`\Ҏ\N:VeroŮԎM<\df| )=آʳ+$qWEREY{dѥd/g"k6U3e?bN/8hfQpbٕC9.Wp& 8;OFlw}hvzŧ9-=;+\!73-/k%%Ty*Yg**eXq8w;0-)eXN«ʰIЏJˋKcQMGJ.R~(sd0RGin"zۻeʚ+ VΡQ"nwxquIQIܘbKhOm#Kf3$̥rAћ|՚B)j̫8P)!bp\G ZFWĠӏ98|>s.T: Zq=?*Iz59If $19ʩ@CyCk^k=Fe*|EjNJHAgXWR"XU]w ( :@a8`Ц,vIxv!9??9 *)e_ظ(( H$z{;U ^džU3'@F"Jf57L$WQB* (Sp0*͠][L3ERc+HJ\( 06v3ȳs* ^`$=ZF#y ݡ &JjΏf fZ4Nˈc9Rh["4D:|$\(q",^6lKn*흴t[SHr@|3&]*xT`ykMckQi2%?eHg D@7ݳ|r7OƵc!IG`)/ *(RV10 ==ooӻҧɷх_qq7YF.N4╴ F DtJ+R]^S,%yGGGx{[}e'6nd̍N3i0bWXpQ'+"[~1g(r]58+IHE`,GIU{v$ raVҶ7yO$;HFIj2PB1Ke+7 )HǎIG;l=5lkW\"bu)ȡD Cmlpbۼ1k3lx.r.Z+tA.ꩊ&L%Ѷvݝ#s e̅_nfe Pna純jĎPPJ*PV(HW/Q:,j,f-J:J7|3.fJ^q'P誡m ;s!pF2N @ k?)7NA;L8fa%i0qQ+^\胨ICEXb8j`ϼ QYj6VEdm!lc'V8"U+zW"`vn &e&^p365AQMcyMuPAdbpz7|$ ՑY #B5N\%+ENv[I:IQiU7MUO]_CzҪ7sn;`IU+JF*AI1xɰDZvrʤER9BH2Nle~&qƓ/Uw,)%5`y^udQAMPN~fm^x^#Ծ҉JzK {-;kW$]2:S$Y&阧Mr6V;3Z!2 Z^rLsdy kL\}Cctblff`ݨߴ0*PVFF׭۫םl\\MOCJJScL;Ch}Pi֘u쪔ZuZeIUDZ$1BL]PGҴ&K>(X&j 7u4&Ab;fB12J3(9\"m&p 2TWDrfp ۔$J$9dP8w{CpӺ#MkI.HRټs˧ۉy˝WYgPG;L@vwrOKi%HR4l}!%"r4t| cfԋWM Q!JC T XXXP ZEDE4n2.1tGI6Y1lREDLP(xr#CmAv٣hQK䚿%ZPzMN),[>3Qnӵ:׫S&a**f,ы}/ JO@QR=OlgcY+\.^ uKqMV1]G[>le 6h?-5y:|%(鬚ܣ'g~ g=gHr,Xf+PZl'Ϊc6lv`^dkF90'#ͼr1[rzN3^f'GHLKyfKG7f`hgKǻy᫕'dHa ~\Tt :mOQŵ1_(UMl4*-/_䘥FDĖL\d=JktRBQ뒬263X썆." QKʚ,xW-y-78wu1h(6jfTǶ/B.ܭܳ3uӖõTJYcHKrbZ!xVPfueNԄ1&/^W^/jK}7bMŮX:;2G--;naAFcNz/E?8E-|yvuk&,Qj읶nγn_)bT DETZ*c4b/Z:ۯg"!YΝeݬO `g enUN>&=UD1k wN;iI{<;R2Ӵ [wgHN&@9S5앦qi @G)wNi8h҉d˧Ym=Bio$- @eA^`;^V Q_F(`5«]#DpʘP#tvGĸasPNI׹IRUc/P69+XK,w]ڽi\wUY jG*CP+p( c6/T\L)1QrfM bj#N+[)hP4W"vrJ<&\m$%v~s>sU11'dqzb"'+qZt+GCV=Z猣1QGη,Ejf8V1jV_QW Rز+^.6 _ԃk3R]>ܲϪHƾʛv,Xl3;Q7ϰ2őPҴE?8ƬٶNgղԬuĺǹҤa s =-[Q2kǵֲ:5Hqjhl]"t[ 3䙝ԆRwEKrLXpmvE\55fb*QNv1Xw/M_GZdn^@ ^:*W/cHm2 ɳy!I2LJ3,,He w^+l;dNI2RevpI;1N^n2U#$[`%NlQL-j/|;Gǝ6=2$l&C*r<"L5+Va|܆#u^;*M'!ަY 2MIWaǃ> M~}mߋ:=v<ͺ>n&dNNA*$nMc֗*)*8QpFHZkuݠD]3UrjE#=!nhƙ*T> J/$8aQeTcWUS,ܸQ=1`X"N@Ok+ 9 *'R]\YTQ%PA(be1s B&Ps!Cyz6b,dIQjt\ow|n -RJ LeEl3Ӝ[ Q\O6 $*8^鴍Awɠ( $,RS<̛R06fͳvL7E6mQIV[TPnJTPn%) lĉׯeVɪNq+ɬpA;fJW ej庅:jC@@DÚpղG5^񂫢tB`w,P3W&bdDQXq26jBlKTPMSw@I$ `B8J8Cw6ŔS6..tm,RpC;2![X [F L:Aހ SPQZ뒮9%d#aR.9Ņ% "uţu# UÕ-UMaR&ʌ-ꍗE^;h$?z3}^S zSLPkA+=q> kfOJa{d^r>-Ȏ粵մ٢I?(]e[ͿoCkF瓖+`7[UIjG?u%m`Ƕ ~J]fΆ샋H\d'&?_[ K YWfo3w{d]4hI\6f& d"D!0z+$Eq4*B)Ep3xFM>NUTo# Tq "]r2shQ?UZZ B9XY +c߶`f'Wo,ئe'.r_\:\8ruxG OYQzԴn w%Cޫ. YCq܋>)H/;ϱ7<Ǒar =r7[YљQnt2*9=HRՆ/$[b)+a^yN]|1 vv ^(I ?O>ݗ-y ZUW *^c/,wT 2_/_뭰g?H-Px^߻:+m$Ȱe)fzpŶ"dyXi[Ew#J'292 2"V,w(\}tT ["CJEM FES9BDžDU˄db2;M铍jmMI ؑ08z`5YTUBE2SnB"e9mDJ2Q )]pl1!d+bsoU!p2bKifZ"GwW n.eզ*sv[|W^QJtVZH0nP<] h1*tRlֹV>\ 7J ;"l5\puI]n7%\Cvь|)9qR+9FSX7pNeg_KL 8ۮGA/vGzߺ<۷D',M}+sX ,^ Y E̗&KEH ֣1 `gY~(qMFA&qAk P碋pB  ˿koy튻Ŵ[\nZlSo3-W#Q)nvQ9ӣbY|Uh zW)1Gۯ4*(^@z"h-U)y(,jjɘ4Tt4bK31ϼElV69v QYŦ"SLU2*jſY8?a|[hweBeۻ{~`߿m}ǻi` n񟐆?B\{?icvR.2fwrZb'b  UN%ݑñMc%0"#_B0V]uXd$͉E,$Tg*$|X5]BD+RmˍIKrƹN؛5QH˻p]ڮa5_?}YdXY 5q<M6.dp|1e|uovjԆӕ6SCvf`UiuL}O.-ӎttf;v(UGL;34BY62ʖ(i[0e){JC$ av*8qBv4]ܫ R:j]s HdLD7)z5O5lVt*$ݱDopsQP E3}LtyLI9K GSH }jP Ąޢhwl R>g,_7Wh/#/ow ^X_Խp:;Tǿ F0ݝjސ=tkX9eLnò:/~>Xr?Z?o3p n\垖7yJCrswy\)W?Oex&~u^/wjy~s?%_ nvy<~z>/^g9{?>^طL)|~w)nN~\pqK+3Cw7y\>W~}U{7˫oﯕ=w-ǻ7٧>ZoX>{נέo3wڡ_;G4Ӯyϛe{Yսj7y՟xaY{NeǕ~v7¯ /.| Ӊ"Kh?ryjY<=>r8s7ͯ&hr"}48mk9[Ǐj#̯ͱY3й;^_{+ٟ|~~|s_.sߏnɾwR 3}W=>+n jך?o؝}K[^W \};sv_ ? be=oď]|![rmzvd7֔_.N_d>|\TW_G`6SQ{Kd>c?[92׼md?x `$>ѿmXwIǡ⟭q#;ߵǩ莩ڕ;ѯby:.OǞH?Nyٜ/~6?A"?;]?c=Er߯g}G> _b>}o_?Acu_yO>~z~y[N./6yX=%quΟMO>T{KHkN7/o=8??x/ocϨ~xXmyO|ٞ0_J~?ldϿzo|'_fm~)?`|Uk?zdvG$sֺ\_?>n~qq{|]z[y=ֿLg~_{?9ǻ4o?muCM?mqv/՝tݖǃ?.WǶ6b:=gc33|gT:׏y~>½g˙O$y+=+_x˳ϕ14y|[zsRĝsн+z~xz1|o|R} _Wz?wG;'?֓Sw?K/H@H Normal CJOJPJQJ_HmH sH tH >@> Heading 1$$@&a$5@@@ Heading 2$$@&a$5>*@@@ Heading 3$$@&a$56>@> Heading 4$$@&a$5DA@D Default Paragraph FontViV  Table Normal :V 44 la (k(No List \\@\ z-Top of Form  OJPJQJmH sH u0U@0 Hyperlink>*B*4B@4 Body Text$a$P+@"P  Endnote Text$dha$CJOJPJQJF>@2F Title$dh1$a$CJ0OJPJQJVOBV Body Style  OJPJQJmH sH u6 H79:r 9:klL<=A B C d f   ' ( @ A B O v w x     | } ~   0 1 2 e f &'()JKLstBCCvw#$_`+,@5800000000000000000000000000000000000000000000(00000000000000000000000000000000000000000000000000000000000000000000000000000000000 h(P\KT6" !" J_6"#6"6X8@0(  B S  ?6,c|LLX d   lM ZddXdMMgmmAb/*urn:schemas-microsoft-com:office:smarttags PostalCode81*urn:schemas-microsoft-com:office:smarttagsCity94*urn:schemas-microsoft-com:office:smarttagsplace?*urn:schemas-microsoft-com:office:smarttags stockticker>6*urn:schemas-microsoft-com:office:smarttags PersonName C6543411/./.4665361441.41.641465341/644136334165341/' 8P S BK83333r :ClC d  ( B x   )JB$88RVo776FA V:8Mi(QyS'1 ZC"F:Zk![uZ[4\4Q^c*bcnrfexn~g56U6hPaOV%ssD| 3{qDhw72-zhw` 1S/LK@'z">7%,+8@6@UnknownGz Times New Roman5Symbol3& : Arial;& z Helvetica[:FONDkP Friz QuadrataCourier New3z TimesQ :FONDDBenguiatCourier Newa0:-University RomanCourier New qhBdžBdž&M /M /$24d)) 2qHX(?sD2Dear Colleague, Peter O'BrienTamsin WilkinsOh+'0  8 D P \hpxDear Colleague,Peter O'Brien Normal.dotTamsin Wilkins2Microsoft Office Word@G@$n_@@M՜.+,D՜.+,L hp  University of York/ )' Dear Colleague, TitleH`h _PID_HLINKS_AdHocReviewCycleID_EmailSubject _AuthorEmail_AuthorEmailDisplayName_ReviewingToolsShownOnceAhBmailto:paob1@york.ac.ukh(RSC Heterocyclic and Synthesis Groupk.hemming@hud.ac.ukKarl Hemming  !"#$&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxz{|}~Root Entry FPےData %$1Tabley*WordDocument.HSummaryInformation(DocumentSummaryInformation8CompObjq  FMicrosoft Office Word Document MSWordDocWord.Document.89q