91AV

The 91AV of Phosphorus that goes into the Large Scale Manufacture of Organophosphine Ligands and Catalysts

27 May 2025 14:00-15:00, United Kingdom


Introduction
Access to industrial scale volumes of alkyl organophosphines, their derivatives, and phosphonium salts are critical to the successful commercialisation of many applications including petrochemical catalysis, pharmaceutical, fragrance, fine chemicals and polymer synthesis. The industrial production and supply of these materials will be the focus of this presentation. The underlying chemistry of phosphorus derivatization will be presented including the generation of phosphine gas and the synthesis of alkylphosphines. This includes atmospheric or high pressure chemistry with radical or acidic initiators as well as coupling chemistry and other synthetic methods.  The discussion will provide insight into how various phosphorus starting materials such as phosphine gas (PH3) and white phosphorus (P4) and the chemistries employed can allow access to a diverse range of very versatile phosphorus-based materials from kilogram to multi ton quantities and how product quality, which is critical to commercial consumers, can be handled.. Product applications to be highlighted include precursors for electronics applications, materials for coatings applications, ligands & catalysis as well as chemistries for thermoset material formulations. The presentation will also cover new product development and scale up.
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United Kingdom

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