Headspace Sampling for Gas Chromatography
Headspace sampling is an ideal way of introducing a sample into a GC. It avoids the introduction of involatile or high-boiling contaminants from the sample matrix and it can often be used for the trace or ultra-trace determination of volatile organics with little or no additional sample preparation. However, there are many factors to consider when developing a headspace-GC method, from correct sampling, matrix modification, optimisation of headspace sampler parameters and techniques for refocusing the analyte band on the analytical column. This short course will introduce you to the important principles and practical considerations of headspace sampling.
• Sampling for headspace analysis
• Fugacity – what it is and why it’s important
• Static and dynamic headspace sampling
• Headspace sampling using SPME
• Optimising headspace sampling parameters
• Optimising GC parameters
Headspace sampling is an ideal way of introducing a sample into a GC. It avoids the introduction of involatile or high-boiling contaminants from the sample matrix and it can often be used for the trace or ultra-trace determination of volatile organics with little or no additional sample preparation. However, there are many factors to consider when developing a headspace-GC method, from correct sampling, matrix modification, optimisation of headspace sampler parameters and techniques for refocusing the analyte band on the analytical column. This short course will introduce you to the important principles and practical considerations of headspace sampling.
• Sampling for headspace analysis
• Fugacity – what it is and why it’s important
• Static and dynamic headspace sampling
• Headspace sampling using SPME
• Optimising headspace sampling parameters
• Optimising GC parameters
